Solution for infusion - 5 g/1000 ml - 100 ml

Metronidazole, a synthetic derivative of nitroimidazole, acts against gram-positive and gram-negative anaerobic microorganisms (Bacteroides species, including the B.fragilis bacterial group, Clostridium species, Eubacterium species, Peptococcus species, Peptostreptococcus species and against protozoan (Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia). The mechanism of action of metronidazole is not yet clear. It is thought that metronidazole inhibits the synthesis of DNA. It has bactericidal action.

Metronidazol is used in:

• the treatment of infections caused by anaerobic microorganisms and infections from protozoa;
• prevention of postoperative infections caused by anaerobic bacteria, especially bacteroides and anaerobic streptococci species;
• the treatment of septicemia, bacteremia, peritonitis, brain abscess, necrotizing pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis and postoperative infections wounds when from them are isolated sensitive anaerobic pathogen microorganisms; urogenital trichomoniasis in females (trichomonial vaginitis) and in males; bacterial vaginosis (also known as non-specific vaginitis), or anaerobic vaginosis or Gardnerella vaginitis;
• acute ulcerative gingivitis; leg ulcers, infected by anaerobic microorganisms;
• acute dental infections (e.g. acute pericoronitis and acute apical infections);
• all forms of amoebiasis (intestinal and extraintestinal disease) and those of asymptomatic cyst holders;
• giardiasis;
• treatment of Helicobacter pylori, in combination with other medicines.