Oral suspension - (200 mg + 40 mg/5 ml)

Tablets - 100 mg

Doxyderma is a broad-spectrum antibiotic of the tetracycline group.

Doxyderma is indicated for infections caused by pathogens sensitive to doxycycline, especially by:

• Infections of therespiratory airways andear-nose-throatarea
• acute exacerbationsof chronicbronchitis
• sinusitis
• inflammation of the middle ear (Otitis media)
• certain forms of pulmonary inflammation (pneumonia)caused by mycoplasma, rickettsia or chlamydia
• Genitourinary tract infections urethritis caused by Chlamydia and Ureaplasma urealyticum
• acute prostatitis
• uncomplicated gonorrhea (especially with concurrent chlamydial infection)
• infections of the female genital organs
• syphilis, when there is penicillin allergy
• urinary tract infection (only in case of proven sensitivity of the pathogen)
• Infections of the gastrointestinal tract
• Cholera
• infections caused by Yersinia or Campylobacter
• Shigella infection in proved sensitivity
• Outpatient treatment of biliary tract infections
• Skin diseases, also infected severe forms of acne vulgaris and rosacea
• Conjunctivitis caused by chlamydia and trachoma
• Diseases caused by Borrelia such as erythema chronicum migrans and Lyme disease (mainly caused by infections from bites)
• Rare infections such as brucellosis, ornithosis, bartonellosis, listeriosis, rickettsiosis, melioidosis, plague, inguinal granuloma
• Other diseases: malabsorption syndrome (diseases associated with dyspepsia) for example tropical Sprue and Whipple's disease.

Tablets - 100 mg

Doxyderma is a broad-spectrum antibiotic of the tetracycline group.

Doxyderma is indicated for infections caused by pathogens sensitive to doxycycline, especially by:

• Infections of therespiratory airways andear-nose-throatarea
• acute exacerbationsof chronicbronchitis
• sinusitis
• inflammation of the middle ear (Otitis media)
• certain forms of pulmonary inflammation (pneumonia)caused by mycoplasma, rickettsia or chlamydia
• Genitourinary tract infections urethritis caused by Chlamydia and Ureaplasma urealyticum
• acute prostatitis
• uncomplicated gonorrhea (especially with concurrent chlamydial infection)
• infections of the female genital organs
• syphilis, when there is penicillin allergy
• urinary tract infection (only in case of proven sensitivity of the pathogen)
• Infections of the gastrointestinal tract
• Cholera
• infections caused by Yersinia or Campylobacter
• Shigella infection in proved sensitivity
• Outpatient treatment of biliary tract infections
• Skin diseases, also infected severe forms of acne vulgaris and rosacea
• Conjunctivitis caused by chlamydia and trachoma
• Diseases caused by Borrelia such as erythema chronicum migrans and Lyme disease (mainly caused by infections from bites)
• Rare infections such as brucellosis, ornithosis, bartonellosis, listeriosis, rickettsiosis, melioidosis, plague, inguinal granuloma
• Other diseases: malabsorption syndrome (diseases associated with dyspepsia) for example tropical Sprue and Whipple's disease.

Tablets - 250 mg

Solution for injection - 40 mg/2 ml (40 000 UI)

Solution for injection - 80 mg/2 ml (80 000 UI)

Gentamycine is a potent bactericidal antibiotic with a wide range activity against both Gram-positive and Gram-negative strains including Staphylococcus aureus, Escherichia coli, Klebsiella, Proteus, and Pseudomonas species.

Gentamycine solution for injection is indicated for the following cases:

• serious infections caused by aeruginosa, Proteus species, E. coli, Klebsiella species, Enterobacter species, Serratia species, Citrobacter species, Staphylococcus species;
• acute and chronic infections of the urinary tract;
• various systemic infections, such as: neonatal sepsis, peritonitis, meningitis;
• bone and soft tissue infections, such as: acute osteomyelitis, wound infections (including burns);
• bacterial septicemia;
• respiratory tract infections;
• empirical therapy for serious unknown infections.

Film-coated tablets - 500 mg

Tablets - 100 mg

Nitrofurantoin is an antibacterial, which belongs to the group of nitrofuranes.

The mechanism of action of nitrofurantoin has not yet been clarified. There is evidence that this substance inhibits a range of enzymatic systems of bacteria and confirmed that it interferes in the early stages of bacterial carbohydrate metabolism, by inhibiting acetyl coenzime A. Nitrofurantoin acts against a broad spectrum of common pathogen microbes of urinary tract. Most strains of Escherichia coli are sensitive; also, most of strains of Klebsiella - Enterobacter are sensitive to nitrofurantoin.

Nitrofurantoine is indicated in prophylaxis and treatment of acute or recurrent, uncomplicated lower urinary tract infections, either spontaneous or following surgical procedures.

Nitrofurantoine is specifically indicated for the treatment of infections when due to susceptible strains of Escherichia coli, Enterococci, Staphylococci, Citrobacter, Klebsiella and Enterobacter. Most strains of Proteus and Serratia are resistant. All Pseudomonas strains are resistant.

Tablets - 250 mg

Tablets - 750 000 UI

Spiramicine is a macrolide antibiotic that has similar uses with erythromycin. Macrolides are weak bases; their activity increases at alkaline pH. Macrolides penetrate into the pleural fluid, in the ascitic fluid, in the middle ear exudates and in the sputum. When the meninges are inflamed, they can enter in the cerebrospinal fluid. Macrolides are used in respiratory tract, urogenital, digestive and skin soft tissue infections, especially when beta-lactamic antibiotics or tetracyclines are contraindicated.

Spiramicine is indicated in:

• the treatment of otorhinolaryngological, bronchopulmonary, stomathological, genital (especially of prostate origin), bone and skin infections;
• the prophylaxis of meningitis by meningococcus;
• the cases when rifampicin is contraindicated;
• the toxoplasmosis of old women.

Tablets - 400 mg + 80 mg