Antiinfectives For Systemic Use

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ATC Reimbursed

List of reimbursed drugs, is an important part of Service Packages covering the Fund of Compulsory Health Care Insurances for the population. The list of reimbursable drugs aims at improving the quality of service for all patients, particularly for people in need. In this regard, through the new list of drugs, FCHC aims at increasing the attention toward categories such as retirees and patients suffering from serious illnesses.

In compiling the list of drugs there are some scientific criteria which have been taken into consideration, by giving priority to drugs used for severe diseases; diseases of high risk for life; diseases that cause disability; diseases that risk of being spread into the society; diseases that cause much suffering as well as chronic illnesses requiring prolonged treatment.

Antiinfectives For Systemic Use - Reimbursed

Concentrate for solution for infusion - 100 mg / 10 ml

Neocil contains the active substance ciprofloxacin (as lactate). Ciprofloxacin is an antibiotic belonging to the fluoroquinolone family. Ciprofloxacin works by killing bacteria that cause infections. It only works with specific strains of bacteria.

Adults

Neocil is used in adults to treat the following bacterial infections:

  • respiratory tract infections;
  • long lasting or recurring ear or sinus infections;
  • urinary tract infections
  • genital tract infections in men and women;
  • gastro-intestinal tract infections and intra-abdominal infections;
  • skin and soft tissue infections;
  • bone and joint infections;
  • anthrax inhalation exposure.

Ciprofloxacin may be used in the management of patients with low white blood cell count (neutropenia) who have a fever that is suspected to be due to a bacterial infection.

If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to Neocil.

Children and adolescents

Neocil is used in children and adolescents under specialist medical supervision to treat the following bacterial infections:

  • lung and bronchial infections in children and adolescents suffering from cystic fibrosis;
  • complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis);
  • anthrax inhalation exposure.

Neocil may also be used to treat other specific severe infections in children and adolescents when your doctor considers this necessary. 

Tablets - 100 mg

Nitrofurantoin is an antibacterial, which belongs to the group of nitrofuranes.

The mechanism of action of nitrofurantoin has not yet been clarified. There is evidence that this substance inhibits a range of enzymatic systems of bacteria and confirmed that it interferes in the early stages of bacterial carbohydrate metabolism, by inhibiting acetyl coenzime A. Nitrofurantoin acts against a broad spectrum of common pathogen microbes of urinary tract. Most strains of Escherichia coli are sensitive; also, most of strains of Klebsiella - Enterobacter are sensitive to nitrofurantoin.

Nitrofurantoine is indicated in prophylaxis and treatment of acute or recurrent, uncomplicated lower urinary tract infections, either spontaneous or following surgical procedures.

Nitrofurantoine is specifically indicated for the treatment of infections when due to susceptible strains of Escherichia coli, Enterococci, Staphylococci, Citrobacter, Klebsiella and Enterobacter. Most strains of Proteus and Serratia are resistant. All Pseudomonas strains are resistant.

Tablets - 250 mg

Tablets - 750 000 UI

Spiramicine is a macrolide antibiotic that has similar uses with erythromycin. Macrolides are weak bases; their activity increases at alkaline pH. Macrolides penetrate into the pleural fluid, in the ascitic fluid, in the middle ear exudates and in the sputum. When the meninges are inflamed, they can enter in the cerebrospinal fluid. Macrolides are used in respiratory tract, urogenital, digestive and skin soft tissue infections, especially when beta-lactamic antibiotics or tetracyclines are contraindicated.

Spiramicine is indicated in:

  • the treatment of otorhinolaryngological, bronchopulmonary, stomathological, genital (especially of prostate origin), bone and skin infections;
  • the prophylaxis of meningitis by meningococcus;
  • the cases when rifampicin is contraindicated;
  • the toxoplasmosis of old women.

Suspension – 40 %

Tablets - 400 mg + 80 mg

Film coated tablets - 500 mg

Zitara film-coated tablets contain the active substance azithromycin dihydrate which is equivalent to 500 mg azithromycin.

Azithromycin belongs to macrolide antibiotics group.

It is indicated in the treatment of infections caused by certain bacteria or other microorganisms, such as:

  • respiratory tract infections (bronchitis, pneumonia, pharyngitis, tonsillitis, sinusitis);
  • ear infections;
  • skin and soft tissue infections;
  • urogenital infections caused by Chlamydia trachomatis.  
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