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ATC

The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of active ingredients of drugs according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties.

ATC code J: Antiinfectives for systemic use is a section of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products.

Antiinfectives For Systemic Use

Oral suspension - 125 mg/5 ml - 120 ml

Mezyl contains the active ingredient metronidazole. Metronidazole, a synthetic derivative of nitroimidazole, is active against several anaerobic gram-positive and gram-negative microorganisms (Bacteroides fragilis and other Bacteroides spp., Clostridium spp., Eubacterium spp., Peptococcus spp., and Peptostreptococcus spp.) and several protozoa (Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia). The mechanism of action of metronidazole is not entirely clear, but it is thought to inhibit DNA synthesis. Metronidazole has a bactericidal action.

It is indicated in:

  • treatment of infections caused by anaerobic microorganisms, and protozoan infections;
  • the prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic Streptococci;
  • treatment of septicaemia, bacteraemia, peritonitis, brain abscesses, necrotizing pneumonia, osteomyelitis, puerperal sepsis, pelvic abscesses, pelvic cellulitis and post-operative wound infections from which pathogenic anaerobes have been isolated, urogenital trichomoniasis in females (trichomonal vaginitis) and in males; bacterial vaginosis (known as nonspecific vaginitis), anaerobic vaginosis or Gardnerella vaginitis;
  • acute ulcerative gingivitis; anaerobically-infected leg ulcers or pressure sores;
  • acute dental infections (e.g. acute pericoronitis and acute apical infections);
  • all forms of amoebiasis (intestinal and extra-intestinal disease) and symptomless cyst passers;
  • giardiasis;
  • eradication of Helicobacter pylori, in combination with other drugs.

Film-coated tablets - 500 mg

Concentrate for solution for infusion - 100 mg / 10 ml

Neocil contains the active substance ciprofloxacin (as lactate). Ciprofloxacin is an antibiotic belonging to the fluoroquinolone family. Ciprofloxacin works by killing bacteria that cause infections. It only works with specific strains of bacteria.

Adults

Neocil is used in adults to treat the following bacterial infections:

  • respiratory tract infections;
  • long lasting or recurring ear or sinus infections;
  • urinary tract infections
  • genital tract infections in men and women;
  • gastro-intestinal tract infections and intra-abdominal infections;
  • skin and soft tissue infections;
  • bone and joint infections;
  • anthrax inhalation exposure.

Ciprofloxacin may be used in the management of patients with low white blood cell count (neutropenia) who have a fever that is suspected to be due to a bacterial infection.

If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to Neocil.

Children and adolescents

Neocil is used in children and adolescents under specialist medical supervision to treat the following bacterial infections:

  • lung and bronchial infections in children and adolescents suffering from cystic fibrosis;
  • complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis);
  • anthrax inhalation exposure.

Neocil may also be used to treat other specific severe infections in children and adolescents when your doctor considers this necessary. 

Concentrate for solution for infusion - 100 mg / 10 ml

Neocil contains the active substance ciprofloxacin (as lactate). Ciprofloxacin is an antibiotic belonging to the fluoroquinolone family. Ciprofloxacin works by killing bacteria that cause infections. It only works with specific strains of bacteria.

Adults

Neocil is used in adults to treat the following bacterial infections:

  • respiratory tract infections;
  • long lasting or recurring ear or sinus infections;
  • urinary tract infections
  • genital tract infections in men and women;
  • gastro-intestinal tract infections and intra-abdominal infections;
  • skin and soft tissue infections;
  • bone and joint infections;
  • anthrax inhalation exposure.

Ciprofloxacin may be used in the management of patients with low white blood cell count (neutropenia) who have a fever that is suspected to be due to a bacterial infection.

If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to Neocil.

Children and adolescents

Neocil is used in children and adolescents under specialist medical supervision to treat the following bacterial infections:

  • lung and bronchial infections in children and adolescents suffering from cystic fibrosis;
  • complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis);
  • anthrax inhalation exposure.

Neocil may also be used to treat other specific severe infections in children and adolescents when your doctor considers this necessary. 

Solution for infusion - 200 mg / 100 ml

Neocil contains the active substance ciprofloxacin (as lactate). Ciprofloxacin is an antibiotic belonging to the fluoroquinolone family. Ciprofloxacin works by killing bacteria that cause infections. It only works with specific strains of bacteria.

Adults

Neocil is used in adults to treat the following bacterial infections:

  • respiratory tract infections;
  • long lasting or recurring ear or sinus infections;
  • urinary tract infections
  • genital tract infections in men and women;
  • gastro-intestinal tract infections and intra-abdominal infections;
  • skin and soft tissue infections;
  • bone and joint infections;
  • anthrax inhalation exposure.

Ciprofloxacin may be used in the management of patients with low white blood cell count (neutropenia) who have a fever that is suspected to be due to a bacterial infection.

If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to Neocil.

Children and adolescents

Neocil is used in children and adolescents under specialist medical supervision to treat the following bacterial infections:

  • lung and bronchial infections in children and adolescents suffering from cystic fibrosis;
  • complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis);
  • anthrax inhalation exposure.

Neocil may also be used to treat other specific severe infections in children and adolescents when your doctor considers this necessary. 

Tablets - 100 mg

Nitrofurantoin is an antibacterial, which belongs to the group of nitrofuranes.

The mechanism of action of nitrofurantoin has not yet been clarified. There is evidence that this substance inhibits a range of enzymatic systems of bacteria and confirmed that it interferes in the early stages of bacterial carbohydrate metabolism, by inhibiting acetyl coenzime A. Nitrofurantoin acts against a broad spectrum of common pathogen microbes of urinary tract. Most strains of Escherichia coli are sensitive; also, most of strains of Klebsiella - Enterobacter are sensitive to nitrofurantoin.

Nitrofurantoine is indicated in prophylaxis and treatment of acute or recurrent, uncomplicated lower urinary tract infections, either spontaneous or following surgical procedures.

Nitrofurantoine is specifically indicated for the treatment of infections when due to susceptible strains of Escherichia coli, Enterococci, Staphylococci, Citrobacter, Klebsiella and Enterobacter. Most strains of Proteus and Serratia are resistant. All Pseudomonas strains are resistant.

Tablets - 250 mg

Tablets - 750 000 UI

Spiramicine is a macrolide antibiotic that has similar uses with erythromycin. Macrolides are weak bases; their activity increases at alkaline pH. Macrolides penetrate into the pleural fluid, in the ascitic fluid, in the middle ear exudates and in the sputum. When the meninges are inflamed, they can enter in the cerebrospinal fluid. Macrolides are used in respiratory tract, urogenital, digestive and skin soft tissue infections, especially when beta-lactamic antibiotics or tetracyclines are contraindicated.

Spiramicine is indicated in:

  • the treatment of otorhinolaryngological, bronchopulmonary, stomathological, genital (especially of prostate origin), bone and skin infections;
  • the prophylaxis of meningitis by meningococcus;
  • the cases when rifampicin is contraindicated;
  • the toxoplasmosis of old women.

Suspension – 40 %

Tablets - 400 mg + 80 mg

Caplsules - 250 mg

 

Film coated tablets - 500 mg

Zitara film-coated tablets contain the active substance azithromycin dihydrate which is equivalent to 500 mg azithromycin.

Azithromycin belongs to macrolide antibiotics group.

It is indicated in the treatment of infections caused by certain bacteria or other microorganisms, such as:

  • respiratory tract infections (bronchitis, pneumonia, pharyngitis, tonsillitis, sinusitis);
  • ear infections;
  • skin and soft tissue infections;
  • urogenital infections caused by Chlamydia trachomatis.  
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Tablets - 0.5 mg

Oral drops solution – (10.000 UI + 10.000 UI) / ml

Tablets - 5 mg

Solution for injection - ( 0.1%) 1 mg/1 ml

Adrenaline is an endogenous substance that is produced in the adrenal medulla and has important physiological effects. It is a potent agonist at both alpha and beta adrenoceptors, although the effect on beta adrenoceptors is more marked, particularly at lower doses.

 The major effects of adrenaline are dose-related and include:

dilatation of the bronchi, narrowing of blood vessels, increased heart rate and contractility (positive chronotropic and inotropic effect) and stimulation at central level. Adrenaline is a histamine antagonist. It is used for the treatment of life emergencies.

Adrenaline is used in acute allergic reactions and anaphylactic shock.

It is also used in advanced cardiac life support.

Cream - (4000 I.U.+2000 I.U.+2 mg+50 mg)/g