Oral suspension - 125 mg/5 ml - 120 ml

Mezyl contains the active ingredient metronidazole. Metronidazole, a synthetic derivative of nitroimidazole, is active against several anaerobic gram-positive and gram-negative microorganisms (Bacteroides fragilis and other Bacteroides spp., Clostridium spp., Eubacterium spp., Peptococcus spp., and Peptostreptococcus spp.) and several protozoa (Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia). The mechanism of action of metronidazole is not entirely clear, but it is thought to inhibit DNA synthesis. Metronidazole has a bactericidal action.

It is indicated in:

• treatment of infections caused by anaerobic microorganisms, and protozoan infections;
• the prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic Streptococci;
• treatment of septicaemia, bacteraemia, peritonitis, brain abscesses, necrotizing pneumonia, osteomyelitis, puerperal sepsis, pelvic abscesses, pelvic cellulitis and post-operative wound infections from which pathogenic anaerobes have been isolated, urogenital trichomoniasis in females (trichomonal vaginitis) and in males; bacterial vaginosis (known as nonspecific vaginitis), anaerobic vaginosis or Gardnerella vaginitis;
• acute ulcerative gingivitis; anaerobically-infected leg ulcers or pressure sores;
• acute dental infections (e.g. acute pericoronitis and acute apical infections);
• all forms of amoebiasis (intestinal and extra-intestinal disease) and symptomless cyst passers;
• giardiasis;
• eradication of Helicobacter pylori, in combination with other drugs.