Film coated tablets - 150 mg + 12.5 mg

 Co-Ultesan is a combination of two active substances, irbesartan and hydrochlorothiazide.

Irbesartan belongs to a group of medicines known as angiotensin II receptors antagonists. Angiotensin II is a substance produced in the body which binds to receptors in blood vessels causing them to tighten. This results in an increase in blood pressure. Irbesartan prevents the binding of angiotensin II to these receptors, causing the blood vessels to relax and the blood pressure to lower.

Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics, that causes increased urine output and so causes a lowering of blood pressure.

The two active ingredients in Co-Ultesan work together to lower blood pressure further than if either was given alone.

Co-Ultesan is used to treat high blood pressure, when treatment with irbesartan or hydrochlorothiazide alone did not provide adequate control of your blood pressure.