Solution for injection - 0.5 mg/ml
Proserine is a compound that inhibits cholinesterase activity and thus prolongs and intensifies the physiological actions of acetylcholine. It probably also has direct effects on skeletal muscle fibres. The anticholinesterase actions of neostigmine are reversible.
After parenteral doses, Proserine is excreted in the urine both as unchanged drug and metabolites.
Neostigmine undergoes hydrolysis by cholinesterases and is also metabolised in the liver.
Proserine is indicated in:
• diagnostication of Myasthenia gravis;
• symptomatic control of Myasthenia gravis;
• as an antidote for non-depolarising neuromuscular blockers after surgery;
• prevention and treatment of postoperative urinary retention.
Solution for injection - (0.1%) 1 mg/1 ml
Sugar-coated tablets – 10 mg
Film-coated tablets – 600 mg
Solution for injection - (0.1%) 1 mg/1 ml
Tablets - 25 mg
