Suppositories - 100 mg

Durilac contains the active substance diclofenac sodium, which is a non-steroidal anti-inflammatory drug (NSAID). Its action is based in the inhibition of cyclooxygenases, which participate in the biosynthesis of prostaglandins. Prostaglandins have an important role in the process of pain, inflammation and chills. Non - steroidal anti-inflammatory drugs inhibit cyclooxygenases-1 and-2 (COX-1 and-2). Inhibition of COX-1 is associated with gastrointestinal side effects, while the inhibition of COX-2 is associated with anti-inflammatory action.

Diclofenac is rapidly absorbed when it is given in the form of rectal suppositories or intramuscular injection. Diclofenac is also absorbed percutaneously. Approximately 99 % of the drug is bound with the plasma proteins. Diclofenac passes in the synovial fluid and in the breast milk. Its plasmatic half life is 1 – 2 hours. It is excreted in the form of glucuronides and sulphates, mainly through urine (65 %) and bile (35 %).

Durilac is used:

• in musculo-skeletal disorders such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis;
• in peri-articular disorders such as bursitis and tendinitis;
• in soft-tissue disorders such as sprains and strains;
• in painful conditions such as renal colic, acute gout, dysmenorrhoea;
• after some surgical procedures.

Solution for injection - 75 mg / 3 ml

Durilac contains the active substance diclofenac sodium, which is a non-steroidal anti-inflammatory drug (NSAID). Its action is based in the inhibition of cyclooxygenases, which participate in the biosynthesis of prostaglandins. Prostaglandins have an important role in the process of pain, inflammation and chills. Non - steroidal anti-inflammatory drugs inhibit cyclooxygenases-1 and-2 (COX-1 and-2). Inhibition of COX-1 is associated with gastrointestinal side effects, while the inhibition of COX-2 is associated with anti-inflammatory action.

Diclofenac is rapidly absorbed when it is given in the form of rectal suppositories or intramuscular injection. Diclofenac is also absorbed percutaneously. Approximately 99 % of the drug is bound with the plasma proteins. Diclofenac passes in the synovial fluid and in the breast milk. Its plasmatic half life is 1 – 2 hours. It is excreted in the form of glucuronides and sulphates, mainly through urine (65 %) and bile (35 %).

Durilac is used:

• in musculo-skeletal disorders such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis;
• in peri-articular disorders such as bursitis and tendinitis;
• in soft-tissue disorders such as sprains and strains;
• in painful conditions such as renal colic, acute gout, dysmenorrhoea;
• after some surgical procedures.

Gel - 1%

Durilac contains the active substance diclofenac sodium, which is a non-steroidal anti-inflammatory drug (NSAID). Its action is based in the inhibition of cyclooxygenases, which participate in the biosynthesis of prostaglandins. Prostaglandins have an important role in the process of pain, inflammation and chills. Non - steroidal anti-inflammatory drugs inhibit cyclooxygenases-1 and-2 (COX-1 and-2). Inhibition of COX-1 is associated with gastrointestinal side effects, while the inhibition of COX-2 is associated with anti-inflammatory action.

Diclofenac is rapidly absorbed when it is given in the form of rectal suppositories or intramuscular injection. Diclofenac is also absorbed percutaneously. Approximately 99 % of the drug is bound with the plasma proteins. Diclofenac passes in the synovial fluid and in the breast milk. Its plasmatic half life is 1 – 2 hours. It is excreted in the form of glucuronides and sulphates, mainly through urine (65 %) and bile (35 %).

Durilac is used:

• in musculo-skeletal disorders such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis;
• in peri-articular disorders such as bursitis and tendinitis;
• in soft-tissue disorders such as sprains and strains;
• in painful conditions such as renal colic, acute gout, dysmenorrhoea;
• after some surgical procedures.

Tablets - 20 mg

Tablets - 250 mg

Tablets - 250 mg

100 mg – Sugar-coated tablets

Solution for injection - (202 mg + 50.5 mg) / 10 ml (2.5%) 

Solution for injection - (202 mg + 50.5 mg) / 10 ml (2.5%)

Solution for injection - (192 mg + 48 mg) / 2 ml (12%)

Solution with drops for local use - 100%

Eugenol has analgesic and antiseptic action and produces local anesthesia.

The bacteriostatic action of Eugenol is against: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans.

It is used in stomatology, frequently mixed with zinc oxide.

It is used for calming toothaches (a dyed cotton is placed inside the cavity of the affected tooth), in temporary dental fillings with zinc oxide and as a constituent in oral hygiene preparations.

It may be used as flavoring agent.

Clove essence has antihelmintic properties.

Tablets - 37.5 mg

Granules for oral solution - 40 mg

Granules for oral solution

Film coated tablets - 400 mg

Film coated tablets - 400 mg

Film coated tablets - 600 mg

Film coated tablets - 600 mg

Oral suspension - 100 mg / 5 ml

Suppositories – 75 mg