Sugar coated tablets - 10 mg

Librian contains the active substance chlordiazepoxide, which like all other benzodiazepines, potentiates the effects of the gamma-aminobutiric acid (GABA) (facilitates the inhibitory neurotransmition of GABA) and of the other inhibitory neurotransmitters, by binding with the specific benzodiazepinic receptors. The potentiation of the effects of GABA causes the inhibition of the central nervous system.

Librian is almost completely absorbed after oral administration. It is highly bound (about 96%) to plasmatic proteins, while its elimination half-life is from 5 to 30 hours. Chlordiazepoxide passes in the cerebrospinal fluid and in breast milk, as also in the placenta. Metabolites pharmacologically active of chlordiazepoxide are: desmethylchlordiazepoxide, demoxepam, desmethyldiazepam and oxazepam. The unchanged drug and the metabolites are excreted through urine, mainly as coniugated metabolites.

Librian sugar-coated tablets are used in the:

• short-term treatment of severe conditions of anxiety and tension, which occur alone or accompanied with insomnia or organic disorders;
• treatment of muscular spasms with a psychogen and neurogen origin;
• relief of symptoms from acute alcohol withdrawal;
• relief of concerns and anxiety before surgical interventions.

Solution for injection - 40 mg/2 ml

Solution for injection - (2%) 20 mg/ml

Solution for injection - (1000 mg + 0.5 mg)/50 ml

Tablets - 10 mg

Lisidigal contains the active substance lisinopril, which belongs to a group of medicines called ACE inhibitors. Lisinopril lowers blood pressure and enables relaxation of the heart muscle.

Lisidigal is used in:

• treatment of high blood pressure (hypertension);
• patients whose heart function is weakened (symptomatic heart failure);
• short-term treatment (6 weeks) of patients whose blood circulation has shown stability within 24 hours of an acute myocardial infarction;
• treatment of kidney disorders in people with high blood pressure who have type 2 diabetes and previous kidney disease (nephropathy).

Tablets - 20 mg

Lisidigal contains the active substance lisinopril, which belongs to a group of medicines called ACE inhibitors. Lisinopril lowers blood pressure and enables relaxation of the heart muscle.

Lisidigal is used in:

• treatment of high blood pressure (hypertension);
• patients whose heart function is weakened (symptomatic heart failure);
• short-term treatment (6 weeks) of patients whose blood circulation has shown stability within 24 hours of an acute myocardial infarction;
• treatment of kidney disorders in people with high blood pressure who have type 2 diabetes and previous kidney disease (nephropathy).

Tablets - 10 mg + 12.5 mg

Lisidigal HCT is a combination of lisinopril with hydrochlorothiazide. Lisinopril is an ACE inhibitor, which lowers blood pressure and relaxes the smooth muscle of the heart. Hydrochlorothiazide is a thiazide diuretic which stimulates urination.

Lisidigal HCT is used:

• for the treament of high blood pressure without any known causes (essential hypertension) in patients whose blood pressure cannot be adequately reduced with lisinopril alone (or hydrochlorothiazide alone). 

Tablets - 20 mg + 12.5 mg

Lisidigal HCT is a combination of lisinopril with hydrochlorothiazide. Lisinopril is an ACE inhibitor, which lowers blood pressure and relaxes the smooth muscle of the heart. Hydrochlorothiazide is a thiazide diuretic which stimulates urination.

Lisidigal HCT is used:

• for the treament of high blood pressure without any known causes (essential hypertension) in patients whose blood pressure cannot be adequately reduced with lisinopril alone (or hydrochlorothiazide alone).

Tablets - 2 mg

Tablets – 10 mg

Tablets - 10 mg

Lorade contains the active substance loratadine, which is part of a group of medicines called antihistamines.

Lorade is used to treat symptoms of allergic rhinitis (e.g. hay fever) and for chronic idiopathic urticaria (hives of unknown origin).

Syrup - 5 mg/5 ml

Film coated tablets - 5 mg

Losartan is an angiotensin II receptor antagonist. Angiotensin II is a chemical in your blood that tightens your blood vessels. Losartan blocks this effect causing the blood vessels to relax and so lowers your blood pressure.

Losartan is indicated:

• for the treatment of hypertension;
• for the treatment of heart failure in combination with diuretics and/or digitalis medicine;
• for the prevention of stroke in hypertensive patients with left ventricular hypertrophy;
• in the treatment of renal disease in hypertensive, type 2 diabetic patients with proteinuria, as part of their antihypertensive treatment. 

Solution for injection - (10%) 200 mg/2 ml

Tablets - 60 mg

Tablets - 15 mg

Luminal contains as active substance phenobarbital, which is part of the group of barbiturates. It may affect the brain activity at different levels, from excitation to mild sedation to hypnosis and coma. High therapeutic doses of barbiturates may produce anesthesia. Overdoses may cause death. Phenobarbital depresses the sensory cortex, decreases motor activity, alters cerebellar function and causes drowsiness, sedation and hypnosis. Barbiturates have poor analgesic activity in subanesthetic doses and may increase the response to painful stimuli. All barbiturates exhibit anticonvulsant action at anesthetic doses. Barbiturates are respiratory depressants. The degree of respiratory depression is dependent upon the dose. Barbiturates are absorbed in varying degrees following oral or parenteral administration. The salts are absorbed faster than the acids. The rate of absorption is increased if sodium salts are given as a dilute solution or taken on an empty stomach. The onset of action ranges from 20 to 60 minutes after oral administration. After intramuscular injection, the onset of action is more rapid, while after intravenous administration the action may start after 5 minutes. Maximal depression of central nervous system may not occur until 15 minutes after intravenous injection.

Luminal is used:

• as long-term treatment of generalised tonic-clonic and focal-cortical seizures;
• as part of the emergency treatment of acute convulsions, including status epilepticus;
• as short-term treatment of insomnia;
• as preanesthetic sedation;
• in the treatment of febrile seizures in children.

Solution for infusion - 200 gr / 1000 ml

Solution for infusion - 200 gr / 1000 ml

Sugar coated tablets - 50 mg

Mebhydrolin is a substance that is part of the group of antihistamines. The antihistamines reduce or inhibit the main actions of histamine in the organism through the reversible and competitive block of the histamine receptors; they do not disactivate histamine or do not prevent its synthesis or release. Mebhidroline presents antimuscarinic, serotonine antagonist properties and local anaesthetic effects. It is used for the symptomatic relief of hypersensitivity reactions, including urticaria and angioedema, rhinitis and conjunctivitis. It is considered as ineffective in asthma.

Mebhidroline sugar-coated tablet 50 mg is indicated in:

• hay fever;
• vasomotor rhinitis;
• bronchial asthma with an allergic origin;
• urticaria;
• exanthema by drugs;
• itching;
• eczema;
• allergic dermatitis and conjunctivitis;
• insect bites;
• Quincke oedema,
• food idiosyncrasias.

Ovules - 200 mg