Gel - 1%
Durilac contains the active substance diclofenac sodium, which is a non-steroidal anti-inflammatory drug (NSAID). Its action is based in the inhibition of cyclooxygenases, which participate in the biosynthesis of prostaglandins. Prostaglandins have an important role in the process of pain, inflammation and chills. Non - steroidal anti-inflammatory drugs inhibit cyclooxygenases-1 and-2 (COX-1 and-2). Inhibition of COX-1 is associated with gastrointestinal side effects, while the inhibition of COX-2 is associated with anti-inflammatory action.
Diclofenac is rapidly absorbed when it is given in the form of rectal suppositories or intramuscular injection. Diclofenac is also absorbed percutaneously. Approximately 99 % of the drug is bound with the plasma proteins. Diclofenac passes in the synovial fluid and in the breast milk. Its plasmatic half life is 1 – 2 hours. It is excreted in the form of glucuronides and sulphates, mainly through urine (65 %) and bile (35 %).
Durilac is used:
Tablets - 300mg
Alopurin is a medicine which inhibits the formation of uric acid (uricostatic).
Alopurin is indicated:
Adults
Oral drops solution – (10.000 UI + 10.000 UI) / ml
Tablets – 100 mg
Alopurin is a medicine which inhibits the formation of uric acid (uricostatic).
Alopurin is indicated:
Adults
Tablets - 500 mg
Granules for oral suspension - 100 mg
Cox-in contains the active substance nimesulide. It belongs to a group of medicines called non-steroidal antiinflammatory drugs (NSAIDs) and has analgesic properties.
Cox-in is used for the treatment of acute pain and menstrual pain.
Nimesulide should only be prescribed as second-line treatment.
