Diazepam

Diazepam
Diazepam Diazepam Diazepam Diazepam
Nervous System
Albania & Kosovo
No
Yes
Yes
SA00071
Diazepam
(0.5%) 10 mg/2 ml
Solution for injection
Diazepam
Box x 100 ampoules
Solution for injection - (0.5%) 10 mg/2 ml … Read more

Solution for injection - (0.5%) 10 mg/2 ml

Diazepam is a long – acting benzodiazepinic preparation. It exerts an anxiolytic, hypno – sedative (hypnotic and sedative), muscle relaxant and anticonvulsant action through the specific benzodiazepinic receptors, the major part of which are found in the lymbic system, hypotalamus, cerebellum and corpus striatum. These receptors and the gamma – aminobutyric acid (GABA) receptors form an anatomical and functional unit. After diazepam is bound with a receptor, then the GABA transmission and the central nervous system inhibition is potentiated. The consequences are manifested with an anticonvulsant and muscle relaxant action. The stimulatory action of serotonine, noradrenaline and acetylcholine neurotransmitters is reduced, because of the increased action of GABA and as a consequence, the anxiolytic, hypnotic and sedative action of diazepam is potentiated.

 Diazepam is used as follows:

Tablets: anxiety conditions, insomnia, muscle spasms, acute alcohol withdrawal syndrome.

Solution for injection: severe anxiety conditions, symptoms of the acute alcohol withdrawal syndrome (delirium tremens), status epilepticus, muscle spasms, tetanus, premedication in anaesthesia.


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