Ointment - 0.005 g/g
Prednisolone acetate is a glucocorticoid that beside systemic use, has also local use. It has anti-inflammatory, hypoallergenic, vasoconstrictor and antiproliferative properties, therefore it is used in inflammatory skin diseases of different origin, since it reduces a few symptoms, eg itching.
The skin absorption of prednisolone has a low rate when applied as an ointment. It has a very low impact on several parameters, such as plasma hydrocortisol levels and urinary excretion of 17-ketosteroids and 17 –hydroxycorticosteroids.
Prednizolon 0.5% is used in several inflammatory diseases:
- contact dermatitis;
- atopic dermatitis;
- photodermatitis, psoriasis;
- local neurodermatitis.